Key result
Off-pump coronary artery bypass resulted in comparable in-hospital mortality (4.71% vs 8.0%) but significantly reduced post-operative bleeding, blood requirement, and ICU stay compared to conventional bypass in patients with left main stem disease.
Observational (n=110)
No
Absolute Event Rate: 4.71% vs 8%
May support off-pump CABG consideration in left main disease; leaves open randomized confirmation before practice change.
There has been increasing interest in the potential benefit of off-pump coronary artery bypass (OPCAB) surgery when compared to conventional coronary artery bypass (CCAB) using cardiopulmonary bypass (CPB) in the presence of critical left main stem (LMS) Disease. A prospective observational study was conducted from January 2006 to June 2012 in the Department of Cardiac Surgery in the National Institute of Cardiovascular Diseases (NICVD), Dhaka. The study included total 110 patients with LMS disease who underwent CABG. 25 cases were done under CPB and 85 cases were done on beating heart. The two groups had similar baseline characteristics including age, sex, risk-factors, comorbid conditions and extent of coronary artery disease. There was no difference between the groups with respect to mortality, but the incidence of post-operative bleeding (p<0.05) , blood requirement (p d0.05), inotropic and ventilatory support, intensive care unit (ICU) care and post-operative hospital stay (p<0.05) were significantly reduced when performing off-pump CABG in this high-risk group of patients.Bangladesh Heart Journal 2015; 30(2) : 61-67
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Mahmood et al. (2016) conducted an observational in Left main stem coronary artery disease (n=110). Off-pump coronary artery bypass (OPCAB) vs. Conventional coronary artery bypass (CCAB) using cardiopulmonary bypass was evaluated on In-hospital mortality. Off-pump coronary artery bypass resulted in comparable in-hospital mortality (4.71% vs 8.0%) but significantly reduced post-operative bleeding, blood requirement, and ICU stay compared to conventional bypass in patients with left main stem disease.
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