Key result
Women with uncomplicated type 1 diabetes exhibited significantly higher arterial stiffness (radial AIx +5.4% vs -8.0%, p<0.0001) than men, which was not influenced by acute clamped hyperglycemia.
Why the study?
Does clamped hyperglycemia affect arterial stiffness differently in men and women with uncomplicated type 1 diabetes mellitus?
Observational (n=41)
Does clamped hyperglycemia affect arterial stiffness differently in men and women with uncomplicated type 1 diabetes mellitus?
Absolute Event Rate: 5.4% vs -8%
p-value: p=<0.0001
Women with type 1 diabetes exhibit higher baseline arterial stiffness than men, which is not acutely modified by clamped hyperglycemia.
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Women with T1DM show higher arterial stiffness independent of acute hyperglycemia; cross-sectional data leave open longitudinal sex-specific risk validation.
Cherney et al. (2013) conducted an observational in Uncomplicated type 1 diabetes mellitus (n=41). Clamped hyperglycemia vs. Baseline / clamped euglycemia was evaluated on Radial augmentation index (AIx) (p=<0.0001). Women with uncomplicated type 1 diabetes exhibited significantly higher arterial stiffness (radial AIx +5.4% vs -8.0%, p<0.0001) than men, which was not influenced by acute clamped hyperglycemia.
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