Key result
In 3215 Japanese adolescents, brachial-ankle pulse wave velocity increased with age, was higher in males, and was primarily determined by age, weight, and blood pressure.
Cross-Sectional (n=3,215)
The establishment of age-specific centile curves for brachial-ankle pulse wave velocity in Japanese adolescents provides reference values that may help estimate early atherosclerotic risk.
baPWV centiles in Japanese adolescents may aid early risk estimation; leaves open prospective validation before wider use.
To obtain data on the brachial-ankle pulse wave velocity (baPWV) distribution during adolescence, a total of 3215 Japanese adolescents ranging from 12 to 18 years of age were studied. The brachial-ankle pulse wave velocity increased substantially with age and was significantly higher in males than in females. Multivariate regression analysis revealed that age, weight, and systolic and diastolic blood pressures were the major determinants of baPWV for both genders. Age-specific centile curves of baPWV were constructed for males and females by regression curve analysis. The proposed distribution curves of baPWV and its derived cutoff values may allow the atherosclerotic risk profile among adolescents of different ages to be more precisely estimated.
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Miyai et al. (2012) conducted a cross-sectional in Adolescents (n=3,215). Brachial-ankle pulse wave velocity (baPWV) was evaluated on baPWV distribution and determinants. In 3215 Japanese adolescents, brachial-ankle pulse wave velocity increased with age, was higher in males, and was primarily determined by age, weight, and blood pressure.
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