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A nonlinear programming approach is developed to estimate process variables and parameters in nonlinear dynamic systems. This approach is used for identification and nonlinear predictive control of a jacketed CSTR with deadtime on the measurements. Studies are performed that illustrate the effects of model structure uncertainty, parameter uncertainty, measurement noise and measurement deadtime uncertainty. This estimation-based approach is shown to be superior to nonlinear predictive control without estimation.
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Sistu et al. (1990) studied this question.