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August 1, 1971Proceedings of the National Academy of SciencesOpen Access

Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

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MPMichael I. PageUniversity of EdinburghWJWilliam P. JencksUniversity of Stirling

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Page et al. (1971) studied this question.

synapsesocial.com/papers/6a11caaccd406dcc8edcd5a0https://doi.org/10.1073/pnas.68.8.1678
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