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February 1, 1978HeartOpen Access

In normal subjects, peak systolic rate of wall thickening (4.6 1-2 cm/s) is less than peak diastolic rate of wall thinning (10.7 + 1-7 cm/s); in ischaemic heart disease, rapid thinning onset precedes mitral valve opening by 50 + 30 ms.

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Why the study?

How do left ventricular wall thickness and dimension changes differ between normal subjects and patients with heart disease on echocardiography?

Population

73 subjects

Comparison

Digitised echocardiography vs Normal subjects compared to patients with…

Design

Cross-sectional

Authors

TTThomas A. TraillDGD G GibsonDBD J Brown

Discussion

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Member takes

Overview

Supports refined echocardiographic differentiation of ischaemic from normal myocardium; hypothesis-generating pending prospective validation.

Structured PICO

How do left ventricular wall thickness and dimension changes differ between normal subjects and patients with heart disease on echocardiography?

P
Population
73 subjects (10 normal subjects and 63 patients with heart disease, including ischaemic heart disease and hypertrophic cardiomyopathy)
I
Intervention
Digitised echocardiography
C
Comparator
Normal subjects compared to patients with ischaemic heart disease or hypertrophic cardiomyopathy
O
Outcome
Relation between transverse left ventricular cavity dimension and posterior wall thickness (including rates of wall thickening/thinning and timing relative to mitral valve opening)surrogate

Cite This Study

Traill et al. (1978) studied this question.

synapsesocial.com/papers/6a11cc5537ecc83ca3fd4003https://doi.org/10.1136/hrt.40.2.162
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