Why the study?
Do ACT, PS-1, ACE, and MTHFR genotypes associate with dementia risk in elderly populations?
Do ACT, PS-1, ACE, and MTHFR genotypes associate with dementia risk in elderly populations?
Polymorphisms in ACT, PS-1, ACE, and MTHFR loci do not appear to be associated with late-onset dementia in this elderly population.
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No association detected in this case-control study; leaves open whether these genotypes influence dementia risk in broader populations.
Tysoe et al. (1997) studied this question.
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