What does this research mean for the field?

During the preejection period prior to aortic valve opening, the human left ventricle typically undergoes a reduction in equatorial diameter and volume, with expansion at the minor equator occurring only under highly abnormal conditions. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 1971Circulation

Dimensional Changes of the Human Left Ventricle Prior to Aortic Valve Opening

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Population

26 patients, including 6 without left ventricular disease, 5 with wall motion disorders secondary to…

Design

Cross-sectional

Authors

JKJoel S. Karliner RBRichard J. Bouchard JGJames H. Gault

Discussion

Member takes

Overview

LV preejection volume loss may bias isovolumic velocity estimates; supports reevaluation of geometry assumptions but needs prospective validation.

Structured PICO

Population

26 patients, including 6 without left ventricular disease, 5 with wall motion disorders secondary to coronary artery disease, 7 with primary myocardial disease, and 8 with mitral regurgitation

Intervention

High-speed biplane cineradiograms exposed in the frontal and lateral projections

Outcome

Left ventricular dimensional changes (equatorial diameter, long axis, and volume) prior to aortic valve openingsurrogate

Reductions in left ventricular shape and volume prior to aortic valve opening are significant and can lead to underestimation of contractile element velocity if not accounted for.

Cite This Study

Karliner et al. (1971) studied this question.

synapsesocial.com/papers/6a11d076dcb035f2f8fd3ba6 https://doi.org/10.1161/01.cir.44.3.312

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September 1, 1971Circulation

Dimensional Changes of the Human Left Ventricle Prior to Aortic Valve Opening

View Full Paper

Ask AI

Bookmark

Population

26 patients, including 6 without left ventricular disease, 5 with wall motion disorders secondary to…

Design

Cross-sectional

Authors

JKJoel S. Karliner RBRichard J. Bouchard JGJames H. Gault

Discussion

Member takes

Overview

LV preejection volume loss may bias isovolumic velocity estimates; supports reevaluation of geometry assumptions but needs prospective validation.

Structured PICO

Population

26 patients, including 6 without left ventricular disease, 5 with wall motion disorders secondary to coronary artery disease, 7 with primary myocardial disease, and 8 with mitral regurgitation

Intervention

High-speed biplane cineradiograms exposed in the frontal and lateral projections

Outcome

Left ventricular dimensional changes (equatorial diameter, long axis, and volume) prior to aortic valve openingsurrogate

Reductions in left ventricular shape and volume prior to aortic valve opening are significant and can lead to underestimation of contractile element velocity if not accounted for.

Cite This Study

Karliner et al. (1971) studied this question.

synapsesocial.com/papers/6a11d076dcb035f2f8fd3ba6 https://doi.org/10.1161/01.cir.44.3.312

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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