Key result
Presence of late gadolinium enhancement in 4 or more segments on cardiac MRI was associated with ventricular arrhythmias with a sensitivity of 73%, specificity of 76%, and AUC of 0.733.
Why the study?
The study sought to correlate segmental late gadolinium enhancement seen on cardiac magnetic resonance imaging with the occurrence of ventricular arrhythmias in hypertrophic cardiomyopathy patients.
Does late gadolinium enhancement on cardiac MRI correlate with the occurrence of ventricular arrhythmias in patients with hypertrophic cardiomyopathy?
Observational (n=57)
Does late gadolinium enhancement on cardiac MRI correlate with the occurrence of ventricular arrhythmias in patients with hypertrophic cardiomyopathy?
In patients with hypertrophic cardiomyopathy, the presence of late gadolinium enhancement in 4 or more segments on cardiac MRI is moderately predictive of ventricular arrhythmias.
This prospective observational study sought to correlate segmental late gadolinium enhancement (LGE) seen in cardiac magnetic resonance imaging with occurrence of ventricular arrhythmias (VAs) in patients with hypertrophic cardiomyopathy. LGE was assessed in a 17-segmental model of heart. Of 57 patients, VAs were present in 26.3% of patients and 10.5% had sustained ventricular tachycardia. LGE was present in 43.9% of patients. Presence of LGE in 4 or more segments was associated with VAs with a sensitivity of 73% and specificity of 76% with area under curve of 0.733 in C-statistics.
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Gangadharakaimal et al. (2023) conducted an observational in Hypertrophic cardiomyopathy (n=57). Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging was evaluated on Occurrence of ventricular arrhythmias (VAs) (AUC 0.733). Presence of late gadolinium enhancement in 4 or more segments on cardiac MRI was associated with ventricular arrhythmias with a sensitivity of 73%, specificity of 76%, and AUC of 0.733.
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