Interleukin 4 selectively expands functional type 1 conventional dendritic cells from bone marrow progenitors

This is the authors' abstract. We don't add key points for this paper.

T cells. Transcriptomic analyses reveal that IL-4 promotes cDC1 proliferation, providing a mechanistic basis for the enhanced output. Together, these findings uncover an unexpected role for IL-4 in driving the development and scalable production of bona fide cDC1s, facilitating mechanistic studies and supporting their future therapeutic application in human disease.