Key result
Prophylactic revascularization before noncardiac surgery fails to reduce postoperative cardiac complications in stable CAD.
Why the study?
Postoperative myocardial infarction carries higher in-hospital mortality after major surgery, prompting elective preoperative coronary revascularizations to minimize complications.
Does routine prophylactic coronary revascularization reduce postoperative cardiac complications in patients with stable coronary artery disease undergoing noncardiac surgery?
Does routine prophylactic coronary revascularization reduce postoperative cardiac complications in patients with stable coronary artery disease undergoing noncardiac surgery?
Routine prophylactic coronary revascularization before noncardiac surgery is not recommended for reducing postoperative cardiac complications in patients with stable coronary artery disease.
Does not support routine revascularization before noncardiac surgery in stable CAD; confirms prior synthesis while leaving open targeted subgroup questions.
INTRODUCTION: About 234 million major surgical procedures are performed each year worldwide, of which >60 million surgeries are performed in the United States. Though postoperative major adverse cardiac complications are relatively low, patients with postoperative myocardial infarction have higher in-hospital mortality. Thus, comprehensive cardiac evaluations, and in some cases, elective coronary revascularizations, are performed prior to surgery with an intent to minimize these complications. In 2009, approximately 4% of all elective percutaneous coronary interventions were performed in preparation for noncardiac surgery. AREAS COVERED: We discuss relevant articles from the last 50 years regarding elective preoperative coronary revascularization prior to noncardiac surgery. EXPERT OPINION: In the early years there was an interest in preemptive revascularization to reduce postoperative cardiac events; however, subsequent studies in patients with stable coronary artery disease have mostly shown that a strategy of routine prophylactic coronary revascularization prior to noncardiac surgery does not reduce postoperative cardiac complications.
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Raghunathan et al. (2020) conducted a review in Stable coronary artery disease undergoing noncardiac surgery. Preoperative coronary revascularization was evaluated on Postoperative cardiac complications. Routine prophylactic coronary revascularization prior to noncardiac surgery in patients with stable coronary artery disease does not reduce postoperative cardiac complications.
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