Key result
Single-procedure PFA and LAAO proves feasible for persistent AF in a high bleeding risk patient.
Why the study?
Can pulsed-field ablation of the pulmonary vein and left atrial posterior wall be combined with left atrial appendage occlusion as a single procedure in a patient with long-standing persistent atrial fibrillation at high hemorrhagic risk?
Can pulsed-field ablation of the pulmonary vein and left atrial posterior wall be combined with left atrial appendage occlusion as a single procedure in a patient with long-standing persistent atrial fibrillation at high hemorrhagic risk?
Pulsed-field ablation for pulmonary vein isolation and posterior wall ablation can be feasibly combined with left atrial appendage occlusion in a single procedure for high-risk patients.
Supports feasibility of single-procedure pulsed-field ablation with left atrial appendage occlusion in high-hemorrhagic-risk AF; leaves open need for prospective trials.
Pulmonary vein isolation and left atrial posterior wall ablation using the Farapulse system, followed by left atrial appendage occlusion, have been achieved as single combined procedure to treat long-standing persistent atrial fibrillation in a patient at high hemorrhagic risk.
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Bianchini et al. (2023) studied this question. Pulsed-field ablation combined with left atrial appendage occlusion was successfully performed as a single procedure for persistent atrial fibrillation in a patient at high hemorrhagic risk.
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