Key result
Concomitant pulmonary vein isolation with pentaspline pulsed-field ablation and left atrial appendage occlusion via internal jugular venous approach is reported for the first time in the US.
Case Report
This report describes the first US experience of concomitant pulmonary vein isolation using pentaspline pulsed-field ablation and left atrial appendage occlusion via an internal jugular venous approach.
Demonstrates feasibility of jugular access for combined pulsed-field PVI and LAAO; leaves open safety, efficacy, and generalizability.
Percutaneous atrial fibrillation (AF) ablation, regardless of energy source utilized, is being widely used as an effective way of treating atrial fibrillation. Pulmonary vein isolation (PVI) remains the cornerstone of any ablation procedure. Percutaneous left atrial appendage (LAA) closure has emerged as an effective stroke prevention strategy in AF patients who have high thromboembolic risk but cannot tolerate long-term anticoagulation. The combined approach of atrial fibrillation ablation and left atrial appendage occlusion (LAAO) in a single procedural setting has recently received approval from the Centers for Medicare & Medicaid Services (CMS).
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Botros et al. (2025) conducted a case report in Atrial fibrillation. Concomitant pulmonary vein isolation with pentaspline pulsed-field ablation and left atrial appendage occlusion via internal jugular venous approach was evaluated. Concomitant pulmonary vein isolation with pentaspline pulsed-field ablation and left atrial appendage occlusion via internal jugular venous approach is reported for the first time in the US.
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