Key result
A new 3-dimensional echocardiography technique showed excellent correlation with MRI for assessing left ventricular end-systolic volumes (r=0.99, P<0.0001) and other cardiac parameters in mice.
Effect estimate: r=0.99
p-value: p=<0.0001
A novel 3D-echocardiography technique provides highly accurate and rapid assessment of LV volumes, mass, and infarct size in mice, comparable to MRI and histology.
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Supports efficient LV assessment in murine models; leaves open human validation before clinical use.
Dawson et al. (2004) studied Normal and chronically infarcted mice. 3-dimensional echocardiography (3D-echo) vs. Magnetic resonance imaging (MRI) and histology was evaluated on Correlation between 3D-echo and MRI for LV end-systolic volumes (r=0.99, p=<0.0001). A new 3-dimensional echocardiography technique showed excellent correlation with MRI for assessing left ventricular end-systolic volumes (r=0.99, P<0.0001) and other cardiac parameters in mice.
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