Key result
Circulating exosomes serve as emerging diagnostic and prognostic markers that can guide clinicians to better diagnosis and management of stroke.
Why the study?
Stroke diagnosis can be facilitated by neuroimaging, but recent advances in molecular detection techniques have highlighted circulating exosomes as emerging diagnostic, prognostic, and therapeutic markers.
This review summarizes the emerging role of circulating exosomes as diagnostic and prognostic markers in stroke.
Answers are grounded in this paper and cite their sources.
Exosome biomarkers merit prospective validation in stroke; leaves open clinical adoption pending rigorous trials.
Stroke is an acute neurologic disorder which can be life-threatening if left untreated or diagnosed late. Various detecting techniques including neurologic imaging of the brain by computed tomography or magnetic resonance imaging can facilitate diagnosis of stroke. However, according to the recent advances in molecular detection techniques, new diagnostic and prognostic markers have emerged. Exosomes as an extra cellar particle are one of these markers which can have useful diagnostic, prognostic, and even therapeutic impact after stroke. We have previously discussed the role of exosomes in cardiovascular disease and in the present review we focus on the most common cerebrovascular disease. The aim of the present review is summarizing the recent diagnostic role of exosomes which are specifically secreted during a stroke and can guide clinicians to better diagnosis of stroke.
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Esfehani et al. (2019) conducted a review in Stroke. Circulating exosomes was evaluated. Circulating exosomes serve as emerging diagnostic and prognostic markers that can guide clinicians to better diagnosis and management of stroke.
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