Female patients hospitalized for acute myocardial infarction experienced persistently higher mortality rates compared to men over a 12-year period (2004 aOR 1.07 vs 2015 aOR 1.11).
Observational
Do female patients experience worse clinical outcomes and lower receipt of invasive therapies after acute myocardial infarction compared with male patients over time?
Women continue to experience lower receipt of invasive therapies and higher in-hospital mortality rates after AMI compared to men, with no improvement in these disparities over a 12-year period.
Effect estimate: aOR 1.07 (2004) vs 1.11 (2015) (95% CI 1.04-1.09 vs 1.07-1.15)
p-value: p=< 0.001
BACKGROUND: Female patients have been shown to experience worse clinical outcomes after acute myocardial infarction (AMI) compared with male patients. However, it is unclear what trend these differences followed over time. METHODS: test was performed to examine the trend of management and in-hospital outcomes over the study period. RESULTS: < 0.001) and these rates have not narrowed over time (2004 vs 2015: aOR, 1.07 95% CI, 1.04-1.09 vs 1.11 [95% CI, 1.07-1.15), with similar observations recorded for major adverse cardiovascular and cerebrovascular events. CONCLUSIONS: In this temporal analysis of AMI hospitalizations over 12 years, we showed lower receipt of invasive therapies and higher mortality rates in women, with no change in temporal trends. There needs to be a systematic and consistent effort toward exploring these disparities to identify strategies to mitigate them.
Matetić et al. (Thu,) 在 Acute myocardial infarction (AMI) 中开展了一项观察性研究。评估了女性与男性在死亡率和主要不良心脑血管事件方面的差异（aOR 1.07 (2004) vs 1.11 (2015), 95% CI 1.04-1.09 vs 1.07-1.15, p=< 0.001）。在为期 12 年的时间里，因急性心肌梗死住院的女性患者的死亡率持续高于男性（2004 aOR 1.07 vs 2015 aOR 1.11）。
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