Key result
Female sex remains linked to a persistent ~11% higher mortality than men after AMI.
Why the study?
Female patients experience worse clinical outcomes after acute myocardial infarction compared with male patients, but trends in these differences over time were unclear.
Do female patients experience worse clinical outcomes and lower receipt of invasive therapies after acute myocardial infarction compared with male patients over time?
Observational
Do female patients experience worse clinical outcomes and lower receipt of invasive therapies after acute myocardial infarction compared with male patients over time?
Women continue to experience lower receipt of invasive therapies and higher in-hospital mortality rates after AMI compared to men, with no improvement in these disparities over a 12-year period.
Answers are grounded in this paper and cite their sources.
Sex disparities in AMI mortality persist without narrowing; leaves open whether targeted interventions can close gaps.
BACKGROUND: Female patients have been shown to experience worse clinical outcomes after acute myocardial infarction (AMI) compared with male patients. However, it is unclear what trend these differences followed over time. METHODS: test was performed to examine the trend of management and in-hospital outcomes over the study period. CONCLUSIONS: In this temporal analysis of AMI hospitalizations over 12 years, we showed lower receipt of invasive therapies and higher mortality rates in women, with no change in temporal trends. There needs to be a systematic and consistent effort toward exploring these disparities to identify strategies to mitigate them.
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Matetić et al. (2021) conducted an observational in Acute myocardial infarction (AMI). Female sex vs. Male sex was evaluated on Mortality rates and major adverse cardiovascular and cerebrovascular events (aOR 1.07 (2004) vs 1.11 (2015), 95% CI 1.04-1.09 vs 1.07-1.15, p=< 0.001). Female patients hospitalized for acute myocardial infarction experienced persistently higher mortality rates compared to men over a 12-year period.
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