Key result
Residence in England and Wales showed greater annual reductions in first MI incidence (men -3.1% and -3.3%) than Scotland (-1.9%) and Northern Ireland (no change) from 1996 to 2005.
Cohort (n=5,190,000)
Yes
Between 1996 and 2005, the UK saw downward trends in first MI incidence and 30-day case fatality, with greater improvements in case fatality than incidence and widening regional inequalities in incidence.
UK regional MI incidence disparities should not yet change practice; hypothesis-generating for policy or socioeconomic drivers.
BACKGROUND: Understanding myocardial infarction (MI) incidence and case fatality trends across the four UK constituent countries is of importance following devolution of the government of health-care services. METHODS: Retrospective cohort study using a primary care database (5.19 million patients) examining trends in incidence of first MI and 30-day case fatality. RESULTS: From 1996 to 2005, the incidence of MI decreased in all countries, but reductions were greater in England (men, -3.1%; women, -2.8%) and Wales (men, -3.3%; women, -4.6%) than in Scotland (men, -1.9%; women, -0.6%) and Northern Ireland (men no change, women, -0.8%) (average annual percentage change). Greater reductions in England and Wales than Scotland and Northern Ireland meant a widening of north-south difference in MI incidence over the study period. Downward trends in 30-day case fatality were found in each country but less regional variation was evident (England men, -12.0%, women, -11.0%; Wales men, -18.4%, women, -12.6%; Scotland men, -9.5%, women, -9.0%; Northern Ireland men, -8.6%, women, -13.0%). CONCLUSION: From 1996 to 2005, downward trends in the incidence of first MI and 30-day case fatality were evident in each constituent country. Greater improvements in case fatality, compared with incidence, were found within each country.
No takes yet. Share an insight, caveat, or question.
Davies et al. (2010) conducted a cohort in Myocardial infarction (n=5,190,000). Residence in UK constituent countries was evaluated on Trends in incidence of first MI and 30-day case fatality. Residence in England and Wales showed greater annual reductions in first MI incidence (men -3.1% and -3.3%) than Scotland (-1.9%) and Northern Ireland (no change) from 1996 to 2005.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: