Why the study?
Does the presence of non-valvular atrial fibrillation increase the risk of stroke recurrence, systemic embolism, or death compared to sinus rhythm in patients with brain infarction?
Population
276 stroke patients with brain infarction treated at a population-based stroke unit.
Comparison
Presence of non-valvular atrial fibrillation vs Presence of sinus rhythm (SR)
Design
Cohort
Follow-up
5 years
Authors
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NVAF signals markedly higher early recurrence and mortality after stroke; leaves open optimal antithrombotic strategies pending randomized trials.
Does the presence of non-valvular atrial fibrillation increase the risk of stroke recurrence, systemic embolism, or death compared to sinus rhythm in patients with brain infarction?
In stroke patients, non-valvular atrial fibrillation is associated with a significantly higher risk of early (1-month) stroke recurrence, systemic embolism, and mortality compared to sinus rhythm, highlighting a critical high-risk window.
Gustafsson et al. (1991) studied this question.
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