Quasi-experiments are similar to randomized controlled trials in many respects, but there are many challenges in designing and conducting a quasi-experiment when internal validity threats are introduced from the absence of randomization. This paper outlines design, measurement and statistical issues that must be considered prior to the conduct of a quasi-experimental evaluation. We discuss challenges for the internal validity of quasi-experimental designs, inclusion/exclusion criteria, treatment and comparator cohort definitions, and the five types of explanatory variables that one must classify prior to analysis. We discuss data collection and confidentiality, statistical power and conclude with analytic issues that one must consider.
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Matthew L. Maciejewski (2018) studied this question.
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