Key result
Cheyne-Stokes respiration affects 58% of HFrEF patients, with E/e' ratio predicting the apnea-hypopnea index.
Why the study?
Risk factors for pathological Cheyne-Stokes respiration in patients with chronic heart failure needed to be determined.
Cross-Sectional (n=47)
Cheyne-Stokes respiration is highly prevalent (58%) in patients with heart failure and LVEF ≤50%, with elevated left ventricular filling pressure (E/e') serving as an independent predictor.
High prevalence in HFrEF supports screening consideration; hypothesis-generating for E/e' role, prospective studies needed.
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Sorokina et al. (2021) conducted a cross-sectional in Chronic heart failure with reduced left ventricular ejection fraction (n=47). Cheyne-Stokes respiration occurred in 58% of patients with heart failure and reduced ejection fraction, with the E/e' ratio acting as an independent predictor of the apnea-hypopnea index (P=0.042).
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