The fully coupled fluid-structure interaction simulation of the Edwards Magna Ease valve showed good agreement with 4D flow MRI measurements, predicting a stroke volume of 99.48 mL compared to 99.91 mL in vivo.
A fully coupled fluid-structure interaction model was developed to assess patient-specific bioprosthetic aortic valve haemodynamics, offering a tool to investigate structural valve deterioration.
Background: Bioprosthetic aortic valves (BPAV) have been increasingly used for surgical aortic valve replacement (SAVR), but long-term complications associated with structural valve deterioration remain a concern. The structural behaviour of the valve and its surrounding haemodynamics play a key role in the long-term outcome of SAVR, and these can be quantitively analysed by means of fluid-structure interaction (FSI) simulation. The aim of this study was to develop a fully coupled FSI model for patient-specific analysis of BPAV haemodynamics. Methods: Using the Edwards Magna Ease valve as an example, the workflow included reconstruction of the aortic root from CT images and the creation of valve geometric model based on available measurements made on the device. Two-way fully coupled FSI simulations were performed under patient-specific flow conditions derived from 4D flow magnetic resonance imaging (MRI), the latter also provided data for model validation. Results: , including wall shear stress and its derivatives on the valve leaflets and in the aortic root. Conclusion: The FSI workflow presented in this study offers a promising tool for patient-specific assessment of aortic valve haemodynamics, and the results may help elucidate the role of haemodynamics in structural valve deterioration.
Yin et al. (Thu,) conducted a other in Bioprosthetic aortic valve replacement (n=1). Fluid-structure interaction (FSI) simulation vs. 4D flow MRI was evaluated on Hemodynamic parameters (stroke volume, maximum jet velocity, peak systolic spatial mean velocity). The fully coupled fluid-structure interaction simulation of the Edwards Magna Ease valve showed good agreement with 4D flow MRI measurements, predicting a stroke volume of 99.48 mL compared to 99.91 mL in vivo.