Key result
Peri-treatment exercise improves cardiorespiratory fitness and may mitigate cardiovascular toxicities from cancer therapies.
Why the study?
Cardiovascular disease is a leading cause of morbidity and mortality in cancer patients due to risk factors and cancer therapy cardiotoxicity, and exercise may counteract these toxicities.
Does exercise training provide cardioprotective effects and maintain cardiovascular reserve in cancer patients?
Does exercise training provide cardioprotective effects and maintain cardiovascular reserve in cancer patients?
Exercise training is a potential strategy to counteract cancer therapy-induced cardiotoxicity, highlighting the need for patient-tailored exercise prescriptions.
Supports exercise integration in cardio-oncology; leaves open optimal protocols and RCTs for confirmation.
Cardiovascular disease is one of the leading causes of morbidity and mortality in persons with cancer. The elevated risk is thought to derive from the combination of cardiovascular risk factors and direct cardiotoxicity from cancer therapies. Exercise may be a potential strategy to counteract these toxicities and maintain cardiovascular reserve. In this article, we review the evidence for the potential cardioprotective effects of exercise training in cancer patients before, during, and following treatment. We also propose a patient-tailored approach for the development of targeted prescriptions based on individual exercise capacity and cardiovascular reserve.
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Zimmerman et al. (2020) conducted a review in Cancer and Cardiovascular Disease. Exercise was evaluated. Exercise training before, during, and following cancer treatment improves cardiorespiratory fitness and may mitigate cardiovascular toxicities associated with cancer therapies.
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