Key result
In patients with ARVD/C, early repolarization was observed in 3% in isolated lateral leads, 7% in inferolateral leads, and 22% in inferior leads, likely representing late depolarization.
Why the study?
What is the frequency and distribution of the early repolarization phenomenon in patients with arrhythmogenic right ventricular dysplasia-cardiomyopathy (ARVD/C)?
Observational (n=360)
What is the frequency and distribution of the early repolarization phenomenon in patients with arrhythmogenic right ventricular dysplasia-cardiomyopathy (ARVD/C)?
The high frequency of early repolarization in inferior leads in ARVD/C patients is likely due to late depolarization rather than true early repolarization.
Inferior early repolarization in ARVD/C likely reflects late depolarization; hypothesis-generating for ECG diagnosis, needing prospective validation.
The case of a 26-year-old male with sudden cardiac arrest due to ventricular fibrillation and the final diagnosis of arrhythmogenic right ventricular dysplasia-cardiomyopathy (ARVD/C) and initial early repolarization phenomenon is presented in detail. An additional analysis of early repolarization in additional 359 patients with ISFC/ESC diagnostic criteria of ARVD/C revealed a frequency within the threshold in healthy volunteers with 3% in isolated lateral leads and 7% in inferolateral leads. The high frequency of electrocardiographic early repolarization limited to inferior leads (22%) is probably due to late depolarization and represents an already reported typical feature of ARVD/C.
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Peters et al. (2008) conducted an observational in Arrhythmogenic right ventricular dysplasia-cardiomyopathy (ARVD/C) (n=360). Early repolarization phenomenon was evaluated on Frequency of early repolarization. In patients with ARVD/C, early repolarization was observed in 3% in isolated lateral leads, 7% in inferolateral leads, and 22% in inferior leads, likely representing late depolarization.
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