This study provides direct evidence of rAAV integration into the host genome of mouse liver, helping to elucidate the mechanisms involved in rAAV integration into tissues in vivo.
No takes yet. Share an insight, caveat, or question.
rAAV integration signals genotoxicity monitoring needs in gene therapy; leaves open human safety translation.
Nakai et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: