Key result
Self-reported number of cigarettes smoked by post-myocardial infarction patients positively correlated with expired carbon monoxide levels at 12 months (r = 0.70).
Why the study?
Does biochemical validation by expired carbon monoxide improve the detection of smoking status compared to self-report alone in post-myocardial infarction patients?
RCT
Double-blind
Does biochemical validation by expired carbon monoxide improve the detection of smoking status compared to self-report alone in post-myocardial infarction patients?
Effect estimate: r = 0.70
Biochemical validation by expired carbon monoxide correlates well with self-reported smoking status but does not substantially increase the detection of smokers in post-MI patients, though it may discourage denial.
Supports self-report validity in post-MI patients; leaves open whether routine CO validation improves detection or warrants practice change.
Self-report is the standard method for assessment of smoking status in the outpatient setting for myocardial infarction (MI) patients. However, the validity of self-report in this patient population has not been previously investigated. Using data from a double-blind, placebocontrolled, randomized trial we examined the validity of self-report for assessment of smoking status in an outpatient setting for MI patients. Smoking was assessed by self-report and biochemical validation by expired carbon monoxide (CO). Abstinence was defined by a selfreport of no cigarettes smoked in the past week and a CO level of less than or equal to 10 parts per million (ppm). At 12 months, number of cigarettes smoked was positively correlated with CO level (r = 0.70). Results show that biochemical validation by CO does not substantially increase the likelihood of detecting smokers in MI patients. However, it may discourage patients from denying their smoking status and therefore should be considered for routine assessment of smoking status in the outpatient cardiac setting. Current clinical guidelines for secondary prevention in myocardial infarction (MI) patients recommend routine assessment of smoking status.1 In clinical trials, biochemical validation in conjunction with self-report is the conventional method for assessment of smoking status.2–4 In the outpatient
No takes yet. Share an insight, caveat, or question.
Grandi et al. (2014) conducted an RCT in Myocardial infarction. Self-report of smoking status vs. Biochemical validation by expired carbon monoxide (CO) was evaluated on Correlation between number of cigarettes smoked and CO level (r = 0.70). Self-reported number of cigarettes smoked by post-myocardial infarction patients positively correlated with expired carbon monoxide levels at 12 months (r = 0.70).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: