Why the study?
Does heart rate variation via cardiac pacing affect pulse wave velocity in elderly subjects?
Population
22 subjects with permanent cardiac pacing, mean age 77.8+/-8.4 years.
Comparison
Cardiac pacing at 5 different frequencies in the… vs Within-subject comparison across the different…
Design
Other, Order of the various frequencies being randomly determined
Follow-up
same session
Key result
Heart rate significantly affected pulse wave velocity in elderly subjects with permanent cardiac pacing (P=0.01), demonstrating that standardizing PWV for heart rate is mandatory.
Authors
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PWV requires heart rate standardization in elderly paced patients; extends evidence for protocol adjustments in vascular research.
RCT (n=22)
Randomized order of frequencies
Does heart rate variation via cardiac pacing affect pulse wave velocity in elderly subjects?
p-value: p=0.01
Heart rate significantly influences pulse wave velocity, highlighting the need to standardize PWV measurements for heart rate in clinical settings.
Lantelme et al. (2002) conducted an RCT in Permanent cardiac pacing (n=22). Cardiac pacing at different frequencies vs. Intra-individual comparison was evaluated on Pulse wave velocity (PWV) (p=0.01). Heart rate significantly affected pulse wave velocity in elderly subjects with permanent cardiac pacing (P=0.01), demonstrating that standardizing PWV for heart rate is mandatory.