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The study aims to describe the clinical characteristics and health challenges of children with sickle cell disease in Kilifi, Kenya.

An observational study of children with sickle cell disease in Kilifi, Kenya

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The study aims to describe the clinical characteristics and health challenges of children with sickle cell disease in Kilifi, Kenya.
Prospective observational study of 124 children with sickle cell disease attending an outpatient clinic.
Assessment of clinical features including splenomegaly, hepatomegaly, and malaria prevalence.
Comparison of mean haemoglobin concentration with non-SCD controls.
33% of children exhibited splenomegaly, while 20% had hepatomegaly.
Mean haemoglobin concentration was 73 g/l, significantly lower than 107 g/l in non-SCD controls (P < 0.001).
39% of children were hospitalized, and there were two reported deaths.

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Observational study describes health impacts of sickle cell disease in children in Kenya, highlighting clinical features.

Sadarangani et al. (2009) studied this question.

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