A comprehensive, multiparametric diagnostic approach and precision medicine are central to identifying and tailoring treatment strategies for hypertrophic cardiomyopathy phenocopies and mimics.
A comprehensive, multiparametric diagnostic approach is essential to differentiate hypertrophic cardiomyopathy from its phenocopies and mimics, enabling tailored precision medicine strategies.
Hypertrophic cardiomyopathy (HCM) is a common myocardial disease defined by increased left ventricular wall thickness unexplained by loading conditions. HCM frequently is caused by pathogenic variants in sarcomeric protein genes, but several other syndromic, metabolic, infiltrative, and neuromuscular diseases can result in HCM phenocopies. This review summarizes the current understanding of these HCM mimics, highlighting their importance across the life course. The central role of a comprehensive, multiparametric diagnostic approach and the potential of precision medicine in tailoring treatment strategies are emphasized.
Bakalakos et al. (Mon,) conducted a review in Hypertrophic cardiomyopathy (HCM) phenocopies and mimics. A comprehensive, multiparametric diagnostic approach and precision medicine are central to identifying and tailoring treatment strategies for hypertrophic cardiomyopathy phenocopies and mimics.
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