Key result
A systematic review of published case reports provided a structured overview of cardiac tumors mimicking hypertrophic cardiomyopathy to the point of misleading the diagnosis.
Why the study?
Cardiac tumors can echocardiographically mimic HCM as phenocopies, but current evidence is limited to scattered case reports.
Can cardiac magnetic resonance differentiate cardiac tumors mimicking hypertrophic cardiomyopathy from true HCM?
Systematic Review
Can cardiac magnetic resonance differentiate cardiac tumors mimicking hypertrophic cardiomyopathy from true HCM?
This systematic review highlights the importance of considering cardiac tumors as phenocopies of hypertrophic cardiomyopathy and the potential role of cardiac magnetic resonance in accurate diagnosis.
Highlights the need for multimodality imaging to distinguish rare cardiac tumors from hypertrophic cardiomyopathy;.
Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disease that presents with cardiac hypertrophy. HCM phenocopies are clinical conditions that are phenotypically undistinguishable from HCM, but with a different underlying etiology. Cardiac tumors are rare entities that can sometimes mimic HCM in their echocardiographic appearance, thus representing an example of HCM phenocopy. At present, only case reports of tumoral HCM phenocopies can be found in literature. In this systematic review, we analyzed all the published cases in which a cardiac tumor mimicked HCM to the point of misleading the diagnosis, providing a structured overview of the currently available evidence on this topic.
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Bombace et al. (2021) conducted a systematic review in Hypertrophic cardiomyopathy phenocopies. Cardiac Magnetic Resonance was evaluated. A systematic review of published case reports provided a structured overview of cardiac tumors mimicking hypertrophic cardiomyopathy to the point of misleading the diagnosis.
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