Key result
Frailty and diastolic dysfunction grade were significantly associated with future cardiovascular events in elderly patients with preserved ejection fraction and ≥1 cardiovascular risk factor (P=0.015).
Why the study?
Do frailty and diastolic dysfunction grade predict future cardiovascular events in elderly patients with preserved ejection fraction and ≥1 risk factor of cardiovascular disease?
Cohort
Do frailty and diastolic dysfunction grade predict future cardiovascular events in elderly patients with preserved ejection fraction and ≥1 risk factor of cardiovascular disease?
p-value: p=0.015
Frailty and diastolic dysfunction grade provide significant prognostic utility for predicting cardiovascular events in elderly patients with preserved ejection fraction.
May aid risk stratification in elderly preserved-EF patients; leaves open prospective validation and intervention trials.
BACKGROUND: High prevalence of frailty and of diastolic dysfunction (DD) in heart failure and high mortality in frail adults have been noted. We characterized frailty by quantifying differences on echocardiography, and assessed the added prognostic utility of frailty and DD grade in an elderly population. METHODS AND RESULTS: =25.5, P=0.015). CONCLUSIONS: Both frailty and DD grade were significantly associated with future cardiovascular events in an elderly population with preserved ejection fraction and ≥1 risk factor of cardiovascular disease.
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Kusunose et al. (2018) conducted a cohort in Elderly population with preserved ejection fraction and ≥1 risk factor of cardiovascular disease. Frailty and Diastolic Dysfunction (DD) grade was evaluated on Future cardiovascular events (p=0.015). Frailty and diastolic dysfunction grade were significantly associated with future cardiovascular events in elderly patients with preserved ejection fraction and ≥1 cardiovascular risk factor (P=0.015).
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