Higher brachial-ankle pulse wave velocity was significantly associated with symptomatic cerebral infarction in patients with type 2 diabetes, with an odds ratio of 2.53 for the highest versus lowest tertile.
Cross-Sectional (n=1,066)
No
Effect estimate: OR 2.53 (95% CI 1.09-5.86)
p-value: p=0.030
BACKGROUND: Recently a new automatic device that measures brachial-ankle pulse wave velocity using an oscillometric method has been developed. However, the practical significance of brachial-ankle pulse wave velocity measurement remains uncertain. The purpose of this study was to examine the association between brachial-ankle pulse wave velocity and symptomatic cerebral infarction in patients with type 2 diabetes. METHODS: One thousand sixty six patients with type 2 diabetes were studied cross-sectionally. Measurements of brachial-ankle pulse wave velocity were made using the automatic device. Logistic regression analysis was used to calculate the odds ratio for cerebral infarction. RESULTS: The presence of symptomatic cerebral infarction was confirmed in 86 patients. In these patients brachial-ankle pulse wave velocity was found to be significantly higher than in patients without cerebral infarction (18.94 +/-; 4.95 versus 16.46 +/-; 3.62 m/s, p < 0.01). The association between brachial-ankle pulse wave velocity and cerebral infarction remained significant after adjustment for traditional risk factors. There was an increasing odds ratio for each tertile of brachial-ankle pulse wave velocity, from the second tertile (odds ratio, 2.28; 95% confidence interval, 1.05 to 4.94), to the third (odds ratio, 2.53; 95% confidence interval, 1.09 to 5.86). CONCLUSION: Overall, we conclude that an increase in brachial-ankle pulse wave velocity is associated with symptomatic cerebral infarction in patients with type 2 diabetes.
Ogawa et al. (Thu,) conducted a cross-sectional in Type 2 diabetes (n=1,066). Brachial-ankle pulse wave velocity (baPWV) vs. Lowest tertile of baPWV was evaluated on Symptomatic cerebral infarction (OR 2.53, 95% CI 1.09-5.86, p=0.030). Higher brachial-ankle pulse wave velocity was significantly associated with symptomatic cerebral infarction in patients with type 2 diabetes, with an odds ratio of 2.53 for the highest versus lowest tertile.