What does this research mean for the field?

Geometric variations in the human carotid artery bifurcation, specifically the shape of the carotid sinus and the angle between branches, significantly determine the extension, location, and duration of flow recirculation and separation zones that are implicated in atherogenesis. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

March 1, 1990Journal of Biomedical Engineering

Numerical flow studies in human carotid artery bifurcations: basic discussion of the geometric factor in atherogenesis

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Why the study?

How do geometric variations in human carotid artery bifurcations affect fluid dynamic variables related to atherogenesis?

Population

Different human carotid artery bifurcation models

Design

Preclinical

Authors

KPKarl PerktoldGraz University of Technology MRMichael ReschUniversity of Stuttgart

Discussion

Member takes

Implication

Geometric variations may modulate carotid atherogenesis via flow separation; leaves open human translation and risk stratification.

Structured PICO

How do geometric variations in human carotid artery bifurcations affect fluid dynamic variables related to atherogenesis?

Population

Different human carotid artery bifurcation models (computational models describing healthy human carotid bifurcation anatomy)

Intervention

Geometric variations (shape of the carotid sinus and the angle between the branches)

Outcome

Flow velocity, flow separation, flow recirculation, and wall shear stress distributionsurrogate

Geometric variations in the carotid bifurcation significantly affect flow separation and recirculation, highlighting the role of local anatomy in atherogenesis.

Cite This Study

Perktold et al. (1990) studied this question.

synapsesocial.com/papers/6a12577cea48cb855a34a079 https://doi.org/10.1016/0141-5425(90)90131-6

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Numerical flow studies in human carotid artery bifurcations: basic discussion of the geometric factor in atherogenesis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Numerical flow studies in human carotid artery bifurcations: basic discussion of the geometric factor in atherogenesis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider