Valvular heart disease and heart-related disease: a bibliometric and visual analysis from 2000 to 2023

BACKGROUND: Previous studies have shown that valvular heart disease (VHD) is closely related to the development of heart-related disease (HRD). However, the current research for the relationship between VHD and HRD is complex and poorly targeted. Meanwhile, these studies lack the support of bibliometric analysis results. OBJECTIVE: Our study focused on a bibliometric analysis of published papers on the relationship between VHD and HRDs. The study also attempted to identify the primary authors, institutions and countries to analyse the status and trends of research on VHD and HRDs. METHODS: The PubMed database was searched for publications on VHD and HRD between 2000 and 2023. Python v3.10.8, R v4.2.2 and VOSviewer v1.6.18 software tools were utilised to perform this bibliometric analysis and visualisation. RESULTS: There were 4,235 qualified publications found in total, with the annual number of publications increasing. According to the analysis of the co-occurrence of keywords, we found that the main research directions are for age, gender, disease diagnosis and treatment. Newly emerging research mainly focuses on heart failure, which is relatively related to VHD. CONCLUSION: These results provided a useful perspective on current research and future prospects for the research on the link between VHD and HRD, which could help researchers to select partners and facilitate their research to elucidate the underlying molecular mechanisms of VHD and HRD, including the causes, prevention, and treatment.