Key result
Post-CABG cardiac rehabilitation linked to decreased ventricular repolarization indices, including Tpe and QTc.
Why the study?
The study was conducted to evaluate the effect of cardiac rehabilitation on electrocardiographic changes in patients undergoing isolated coronary artery bypass grafting.
Does a cardiac rehabilitation program improve ventricular repolarization indices in patients following isolated coronary artery bypass grafting?
Cohort (n=625)
Does a cardiac rehabilitation program improve ventricular repolarization indices in patients following isolated coronary artery bypass grafting?
Participation in a cardiac rehabilitation program after coronary artery bypass grafting significantly improves electrocardiographic markers of ventricular repolarization, which may reduce the risk of postoperative ventricular arrhythmias.
May support cardiac rehab to improve repolarization post-CABG; hypothesis-generating, needs RCTs to confirm arrhythmia benefit.
BACKGROUND: The aim of this study was to evaluate the effect of cardiac rehabilitation on electrocardiographic changes in patients undergoing isolated coronary artery bypass grafting. METHODS: Between January 2016 and July 2019, a total of 625 patients (485 males, 140 females; mean age: 59.6 years; range, 50.6 to 68.6 years) who underwent isolated coronary artery bypass grafting and survived were retrospectively analyzed. The patients were divided into two groups according to the participation in the cardiac rehabilitation program as follows: the Rehab(+) group (n=363) and the Rehab(-) group (n=262). Electrocardiographic parameters of both groups were compared. RESULTS: There was a significant decrease in the electrocardiographic findings of heart rate (p<0.001), QTc (p<0.001), Tpe duration (p<0.001), Tpe/QT ratio (p<0.001), and Tpe/QTc ratio (p<0.001) in the Rehab(+) group before and after surgery. There was a significant decrease in the Rehab(+) group, compared to the Rehab(-) group, in terms of parameters of QT interval (p=0.001), QTc (p=0.017), Tpe duration (p<0.001), Tpe/QT ratio (p<0.001), and Tpe/QTc ratio (p<0.001). CONCLUSION: Cardiac rehabilitation program after coronary artery bypass grafting decreases ventricular repolarization indices of electrocardiography. Based on these changes, postoperative cardiac rehabilitation program may reduce the risk of ventricular arrhythmia and sudden cardiac death during follow-up.
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Taşbulak et al. (2021) conducted a cohort in Isolated coronary artery bypass grafting (n=625). Cardiac rehabilitation program vs. No cardiac rehabilitation program was evaluated on Electrocardiographic parameters (QT interval, QTc, Tpe duration, Tpe/QT ratio, Tpe/QTc ratio) (p=<0.001). Cardiac rehabilitation after coronary artery bypass grafting significantly decreased ventricular repolarization indices, including Tpe duration (p<0.001) and QTc (p=0.017), compared to no rehabilitation.
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