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September 4, 2006HeartOpen Access

Prognosis of stable angina pectoris: why we need larger population studies with higher endpoint resolution

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Key result

Stable angina remains a high-risk diagnosis in patients with recent-onset symptoms, highlighting the need for larger population-based studies to define prognostic differences across phenotypes.

Population

Patients with stable angina pectoris

Design

Editorial

Authors

ATAdam TimmisInterventional CardiologyGFGene FederUniversity of BristolHarry HemingwayHarry HemingwayPreventive Cardiology

Discussion

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Implication

Highlights the discrepancy in stable angina prognosis between clinical trials and real-world cohorts, calling for larger population studies with higher endpoint resolution.

Structured PICO

P
Population
Patients with stable angina pectoris

Highlights the discrepancy in stable angina prognosis between clinical trials and real-world cohorts, calling for larger population studies with higher endpoint resolution.

Limitations

  • Absence of agreed case definitions for stable angina complicates comparisons between studies

Cite This Study

Timmis et al. (2006) conducted an editorial in Stable angina pectoris. Stable angina remains a high-risk diagnosis in patients with recent-onset symptoms, highlighting the need for larger population-based studies to define prognostic differences across phenotypes.

synapsesocial.com/papers/6a125c7c8edbaba0bf671b58https://doi.org/10.1136/hrt.2006.103119
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The initial management of stable angina in Europe, from the Euro Heart Survey2005 · 85 citations
  2. 2Endothelial Function Predicts Future Development of Coronary Artery Disease2004 · 350 citations
  3. 3Angiotensin-Converting–Enzyme Inhibition in Stable Coronary Artery Disease2004 · 1,130 citations
  4. 4Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146 538 participants in 54 observational studies2006 · 1,362 citations
  5. 5Outcome of stable angina in a working population: the burden of sickness absence2007 · 29 citations