Key result
Patients with acute exacerbation of chronic obstructive pulmonary disease had significantly higher arterial stiffness compared to healthy controls (1859.17 vs 1215.80 dyne.sec.cm-5, p=0.002).
Why the study?
Is acute exacerbation of COPD associated with increased arterial stiffness compared to healthy controls?
Cross-Sectional (n=46)
No
Is acute exacerbation of COPD associated with increased arterial stiffness compared to healthy controls?
Absolute Event Rate: 1859.17% vs 1215.8%
p-value: p=0.002
Acute exacerbation of COPD is associated with significantly increased arterial stiffness and reduced arterial elasticity compared to healthy controls, particularly in patients with moderate to severe hypoxemia.
Acute COPD exacerbations were associated with higher arterial stiffness; cross-sectional data leave open prognostic and therapeutic implications.
Objective: Acute exacerbation in chronic obstructive pulmonary disease (COPD) can result in a major systemic effect due to hypoxemia and systemic inflammation. In our study, we investigated the effects of acute exacerbation of COPD on arterial stiffness (AS) in patients admitted to our hospital.
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Özyılmaz et al. (2014) conducted a cross-sectional in Acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD) (n=46). Acute exacerbation of COPD vs. Healthy volunteers was evaluated on Arterial stiffness (dyne.sec.cm-5) (p=0.002). Patients with acute exacerbation of chronic obstructive pulmonary disease had significantly higher arterial stiffness compared to healthy controls (1859.17 vs 1215.80 dyne.sec.cm-5, p=0.002).
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