Drug Administration Schedules

Common current practice is to prescribe psychotropic drugs so that a specified daily amount is administered in equally divided doses on a three to six times a day schedule. The authors contend that this procedure rests on no valid scientific basis. They cite a number of pharmacologic facts to bolster this conclusion and review the effects and effectiveness of various schedules of drug administration. They conclude that revisions can be made in the present methods of drug administration that result in great pragmatic benefit without loss of therapeutic effect.