Why the study?
How do plasma renin substrate and plasma renin activity levels differ in patients with steroid excess syndromes compared to normal subjects?
Population
Normal subjects and patients with steroid excess syndromes
Design
Cross-sectional
Authors
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May confound renin assays in steroid excess; cross-sectional data leaves open effects on hypertension evaluation.
How do plasma renin substrate and plasma renin activity levels differ in patients with steroid excess syndromes compared to normal subjects?
Steroid excess syndromes, except primary aldosteronism, significantly elevate plasma renin substrate without suppressing plasma renin activity.
Lawrence R. Krakoff (1973) studied this question.
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