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April 7, 1972Science

Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens

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Authors

Bruce N. Ames
Bruce N. AmesUniversity of BernPSPeter SimsUniversity of CambridgePGP.L. GroverRuhr University Bochum

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Ames et al. (1972) studied this question.

synapsesocial.com/papers/6a126a16ea48cb855a34cb98https://doi.org/10.1126/science.176.4030.47
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Frameshift Mutagenesis in Salmonella1966 · 219 citations
  2. 2The metabolism of benz[a]anthracene and dibenz[a,h]anthracene and their 5,6-epoxy-5,6-dihydro derivatives by rat-liver homogenates1965 · 130 citations
  3. 3Genetic deletions at specific loci by polycyclic hydrocarbons in relation to carcinogenesis1970 · 24 citations
  4. 4Mutagenicity to Mammalian Cells of Epoxides and Other Derivatives of Polycyclic Hydrocarbons1971 · 167 citations