What question did this study set out to answer?

To evaluate the contralateral ears of patients with cholesteatoma and assess whether contralateral tympanic membrane findings correlate with specific cholesteatoma growth patterns.

January 1, 2018BioMed Research InternationalOpen Access

The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis

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Authors

LRLetícia Petersen Schmidt Rosito NSNeil M. Sperling ATAdriane Ribeiro Teixeira

Discussion

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Overview

Cross-sectional study finds high rates of matching tympanic membrane retractions in contralateral ears of cholesteatoma patients, indicating retractions drive early disease pathogenesis.

Key Points

To evaluate the contralateral ears of patients with cholesteatoma and assess whether contralateral tympanic membrane findings correlate with specific cholesteatoma growth patterns.
Analyzed videotoscopy findings in both ears of 432 patients with cholesteatoma categorized as posterior epitympanic, posterior mesotympanic, two routes, or undetermined.
Classified tympanic membrane (TM) retractions by location and severity, and evaluated TM perforations for signs of prior retraction.
TM retraction was the most common abnormality detected in the contralateral ear (42.6%), while contralateral cholesteatoma was present in 17.4% of patients.
In posterior epitympanic cases, contralateral retractions occurred more often in the pars flaccida (66.7%) than pars tensa (1.4%), whereas two-route cholesteatoma predominantly involved both sites (65.6%; p < 0.0001).

Cite This Study

Rosito et al. (2018) studied this question.

synapsesocial.com/papers/6a127111ea48cb855a34d7e6 https://doi.org/10.1155/2018/9817123

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January 1, 2018BioMed Research InternationalOpen Access

The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis

View Full Paper

Ask AI

Bookmark

Authors

LRLetícia Petersen Schmidt Rosito NSNeil M. Sperling ATAdriane Ribeiro Teixeira

Discussion

Member takes

Overview

Cross-sectional study finds high rates of matching tympanic membrane retractions in contralateral ears of cholesteatoma patients, indicating retractions drive early disease pathogenesis.

Key Points

To evaluate the contralateral ears of patients with cholesteatoma and assess whether contralateral tympanic membrane findings correlate with specific cholesteatoma growth patterns.
Analyzed videotoscopy findings in both ears of 432 patients with cholesteatoma categorized as posterior epitympanic, posterior mesotympanic, two routes, or undetermined.
Classified tympanic membrane (TM) retractions by location and severity, and evaluated TM perforations for signs of prior retraction.
TM retraction was the most common abnormality detected in the contralateral ear (42.6%), while contralateral cholesteatoma was present in 17.4% of patients.
In posterior epitympanic cases, contralateral retractions occurred more often in the pars flaccida (66.7%) than pars tensa (1.4%), whereas two-route cholesteatoma predominantly involved both sites (65.6%; p < 0.0001).

Cite This Study

Rosito et al. (2018) studied this question.

synapsesocial.com/papers/6a127111ea48cb855a34d7e6 https://doi.org/10.1155/2018/9817123

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