Radiation Induced Neoplasia Following External Beam Therapy for Children With Retinoblastoma

Radiation induced neoplasia was assessed in a uniform population—children treated with irradiation for retinoblastoma. The incidence of radiation induced neoplasia varied with dose, and is estimated to be approximately 1.5 per cent with current techniques (megavoltage, 3,500 rads in 18-20 days, treatment three times a week). There was no direct correlation of dose with latent period.