What question did this study set out to answer?

This research aims to understand the neuroanatomy underlying impulsivity and response inhibition in bipolar disorder during mania.

October 23, 2008Early Intervention in PsychiatryOpen Access

Magnetic resonance imaging brain activation in first‐episode bipolar mania during a response inhibition task

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Authors

SSStephen M. StrakowskiRutgers, The State University of New Jersey CACaleb M. AdlerUniversity of Cincinnati Medical Center MCMichael A. CerulloUniversity of Kentucky

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Implication

Randomized trial examines brain activation differences in bipolar mania during response inhibition tasks, suggesting distinct neuroanatomic approaches.

Key Points

This research aims to understand the neuroanatomy underlying impulsivity and response inhibition in bipolar disorder during mania.
Examined 16 first-episode manic bipolar patients and 16 matched healthy subjects using functional MRI.
Subjects performed a response inhibition task while brain activity was recorded.
Brain imaging data were analyzed using analysis of functional neuroimages.
Both groups had similar task performance with poor target response rates but high successful 'stops'.
Healthy subjects showed greater activation in regions such as anterior and posterior cingulate and precuneus.
Bipolar patients exhibited specific activation in the prefrontal cortex that was absent in healthy controls.

Cite This Study

Strakowski et al. (2008) studied this question.

synapsesocial.com/papers/6a127baa45487b7639a6934e https://doi.org/10.1111/j.1751-7893.2008.00082.x

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Implication

Randomized trial examines brain activation differences in bipolar mania during response inhibition tasks, suggesting distinct neuroanatomic approaches.

Magnetic resonance imaging brain activation in first‐episode bipolar mania during a response inhibition task

Discussion

Member takes

Implication

Key Points

Cite This Study

Magnetic resonance imaging brain activation in first‐episode bipolar mania during a response inhibition task

Discussion

Member takes

Implication

Key Points

Cite This Study

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