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January 19, 2009Canadian Medical Association JournalOpen Access

Avoiding hospital admission through provision of hospital care at home: a systematic review and meta-analysis of individual patient data

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Key result

Avoiding hospital admission through the provision of hospital care at home significantly reduced mortality at 6 months (HR 0.62) compared to inpatient care for selected patients.

Why the study?

Does hospital care at home reduce mortality and hospital admissions compared to inpatient care in patients requiring acute hospital admission?

Population

10 randomized trials in systematic review, 5 trials in meta-analysis. Patients aged 18 years and older with…

Comparison

Hospital care at home vs Inpatient care in an acute care hospital

Design

Meta-analysis, Randomized controlled trials, Blinded assessment of outcome was…

Follow-up

1 week to 12 months

Authors

SSSasha ShepperdUniversity of OxfordHDHelen DollFolkestone CollegeRARobert AngusUniversity of Liverpool

Discussion

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Implication

Supports hospital-at-home for selected acute patients; confirms mortality benefit and extends evidence for scalable alternatives to inpatient care.

Study Design

Type

Meta-Analysis (n=1,327)

Multicenter

Yes

Structured PICO

Does hospital care at home reduce mortality and hospital admissions compared to inpatient care in patients requiring acute hospital admission?

P
Population
10 randomized trials (1327 patients) in systematic review, 5 trials (844 patients) in meta-analysis. Patients aged 18 years and older with conditions requiring acute hospital admission (e.g., COPD, stroke, acute medical conditions, cellulitis, pneumonia, dementia), average age 70 to over 80 years.
I
Intervention
Hospital care at home (active treatment by health care professionals in the patient's home as a substitute for inpatient care)
C
Comparator
Inpatient care in an acute care hospital
O
Outcome
Mortality at 3 months and 6 monthshard clinical

Main Result

Effect estimate: HR 0.62 (95% CI 0.45-0.87)

p-value: p=0.005

For selected patients, avoiding admission through provision of hospital care at home yields similar or better mortality outcomes and greater patient satisfaction compared to inpatient care, at a similar or lower cost.

Limitations

  • Each of the included trials was individually underpowered
  • Cannot rule out the existence of publication bias
  • Low numbers of patients recruited to the included trials
  • Blinded assessment of outcomes was not possible
  • Small numbers of patients recruited to trials
  • Potential publication bias
  • Variation in the way hospital-at-home schemes operated
  • Some patients required access to hospital services

Cite This Study

Shepperd et al. (2009) conducted a meta-analysis in Acute medical conditions requiring hospital admission (n=1,327). Hospital care at home vs. Inpatient hospital care was evaluated on Mortality at 6 months (HR 0.62, 95% CI 0.45-0.87, p=0.005). Avoiding hospital admission through the provision of hospital care at home significantly reduced mortality at 6 months (HR 0.62) compared to inpatient care for selected patients.

synapsesocial.com/papers/6a128d298edbaba0bf67800fhttps://doi.org/10.1503/cmaj.081491
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