Why the study?
What are the electrocardiographic and electrophysiological characteristics of atrial fibrillation that organizes into atrial flutter during oral class I antiarrhythmic agent therapy?
Population
72 consecutive patients receiving oral class I antiarrhythmic agents for termination or prophylaxis of AF…
Comparison
Oral administration of class I antiarrhythmic… vs Patients without atrial flutter during class I…
Design
Cohort
Authors
Loading...
Coarse AF waves may flag flutter risk on class I agents; hypothesis-generating for ECG-guided hybrid therapy trials.
What are the electrocardiographic and electrophysiological characteristics of atrial fibrillation that organizes into atrial flutter during oral class I antiarrhythmic agent therapy?
Patients with coarse AF on surface ECG and relatively organized right atrial activation are more likely to develop atrial flutter during class I antiarrhythmic therapy, which may help identify candidates for hybrid pharmacologic and ablative therapies.
Ohmura et al. (2003) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: