Why the study?
Do procainamide, isoproterenol, and vagal stimulation alter the electrophysiologic mechanisms and transitions of atrial flutter and fibrillation in dogs with sterile pericarditis?
Do procainamide, isoproterenol, and vagal stimulation alter the electrophysiologic mechanisms and transitions of atrial flutter and fibrillation in dogs with sterile pericarditis?
In a canine pericarditis model, transitions between atrial fibrillation and flutter occur within the same right atrial circus movement substratum, modulated by conduction properties and autonomic tone.
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Highlights pharmacologic/autonomic modulation of AF/flutter transitions in pericarditis model; leaves open human translation.
Pagé et al. (1991) studied this question.
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