Key result
An elevated pre-procedural C-reactive protein level was independently associated with an increased risk of atrial fibrillation recurrence after catheter ablation (HR 2.23; 95% CI 1.04-4.35).
Why the study?
Does an elevated pre-existent C-reactive protein level predict the recurrence of atrial fibrillation in patients with atrial fibrillation undergoing catheter ablation?
Population
257 consecutive patients with atrial fibrillation undergoing catheter ablation
Comparison
Elevated pre-existent C-reactive protein level vs Lower or non-elevated C-reactive protein level
Design
Cohort
Authors
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May refine post-ablation risk stratification; leaves open whether CRP-guided interventions improve outcomes.
Cohort (n=257)
Does an elevated pre-existent C-reactive protein level predict the recurrence of atrial fibrillation in patients with atrial fibrillation undergoing catheter ablation?
Effect estimate: HR 2.23 (95% CI 1.04-4.35)
Elevated pre-procedural C-reactive protein is an independent predictor of atrial fibrillation recurrence following catheter ablation, suggesting a role for inflammation in atrial remodeling and re-entrant substrate.
Kurotobi et al. (2010) conducted a cohort in Atrial fibrillation (n=257). Elevated C-reactive protein was evaluated on Recurrence of atrial fibrillation after catheter ablation (HR 2.23, 95% CI 1.04-4.35). An elevated pre-procedural C-reactive protein level was independently associated with an increased risk of atrial fibrillation recurrence after catheter ablation (HR 2.23; 95% CI 1.04-4.35).
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