Key result
Simultaneous high-resolution mapping of the right atrium confirmed endo-epicardial asynchrony of up to 50 ms during sinus rhythm, highlighting its role in focal activation and atrial fibrillation.
Why the study?
Electrical activity mapping has been investigated to unravel the pathophysiology of AF, particularly the role and mechanisms of focal patterns of activation and endo-epicardial asynchrony.
Design
Review
Authors
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Should not yet change AF ablation practice; leaves open whether targeting endo-epicardial asynchrony improves outcomes.
High-resolution mapping reveals that endo-epicardial asynchrony and focal activation patterns play a key role in the pathophysiology and development of atrial fibrillation.
Groot et al. (2019) conducted a review in Atrial fibrillation. Simultaneous high-resolution mapping was evaluated. Simultaneous high-resolution mapping of the right atrium confirmed endo-epicardial asynchrony of up to 50 ms during sinus rhythm, highlighting its role in focal activation and atrial fibrillation.
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