What does this research mean for the field?

Surgical correction of obstructive lesions of the left ventricular outflow tract, utilizing temporary cardiopulmonary bypass and techniques tailored to anatomic location, can be performed with acceptable risk and yields excellent functional results. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To review diagnostic classification, operative techniques, and surgical outcomes for patients undergoing correction of obstructive lesions of the left ventricular outflow tract.

April 1, 1965CirculationOpen Access

Obstructive Lesions of the Left Ventricular Outflow Tract

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Why the study?

Does surgical correction using cardiopulmonary bypass improve functional results in patients with obstructive lesions of the left ventricular outflow tract?

Population

296 patients with obstructive lesions of the left ventricular outflow tract

Design

Case_series

Authors

DCDenton A. CooleyInterventional / Structural Cardiology ABArthur C. BeallGeorgia Institute of Technology GHGrady L. HallmanTexas Children's Hospital

Discussion

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Implication

Early series support bypass-enabled LVOT surgery in suitable patients; leaves open need for modern prospective validation.

Key Points

To review diagnostic classification, operative techniques, and surgical outcomes for patients undergoing correction of obstructive lesions of the left ventricular outflow tract.
Reviewed clinical outcomes in a surgical series of N=296 patients treated for left ventricular outflow tract obstruction since 1956.
Employed temporary cardiopulmonary bypass with a pump oxygenator for sustained circulatory support during anatomic repair tailored to lesion location and etiology.
Classified outflow tract obstructions into supravalvular, valvular (congenital vs. acquired), and subvalvular stenosis to direct location-specific surgical strategies.
Demonstrated that surgical correction across all anatomic categories is achievable with acceptable operative risk and excellent functional results.

Structured PICO

Does surgical correction using cardiopulmonary bypass improve functional results in patients with obstructive lesions of the left ventricular outflow tract?

Population

296 patients with obstructive lesions of the left ventricular outflow tract (supravalvular, valvular, and subvalvular stenosis, congenital and acquired)

Intervention

Surgical correction using temporary cardiopulmonary bypass with a pump oxygenator

Outcome

Operative risk and functional results

Surgical correction of left ventricular outflow tract obstruction using cardiopulmonary bypass can be performed with acceptable risk and excellent functional outcomes.

Cite This Study

Cooley et al. (1965) studied this question.

synapsesocial.com/papers/6a12932bea48cb855a351bec https://doi.org/10.1161/01.cir.31.4.612

Topics

Congenital heart disease adults

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Obstructive Lesions of the Left Ventricular Outflow Tract

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Obstructive Lesions of the Left Ventricular Outflow Tract

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider