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Systematic review and meta-analysis reveals higher FDG uptake correlates with worse outcomes in HCC, suggesting further investigation is needed.
BACKGROUND & AIMS: F-FDG PET/CT in HCC. METHODS: statistic. RESULTS: F-FDG PET/CT remained consistent across various PET/CT parameters, including SUVmax, tumor-to-liver ratio, and visual assessment of PET/CT positivity, and curative/non-curative therapeutic modalities, all demonstrating that higher FDG uptake is associated with poorer clinical outcomes. CONCLUSIONS: F-FDG PET/CT-based risk stratification. PROSPERO ID: CRD42025633333. IMPACT AND IMPLICATIONS: F-FDG PET-CT for patient selection and as a prognostic tool should be further investigated.
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Min et al. (2026) studied this question.
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