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May 24, 2026Rinsho ShinkeigakuOpen Access

Hemiplegic migraine: from historical perspectives to current management

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Authors

MSMamoru ShibataKSKazumasa SaigohDDDaisuke Danno

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Overview

Randomized trial investigates treatment options for hemiplegic migraine, highlighting potential benefits of CGRP antibodies.

Key Points

  • To explore the characteristics and management strategies for hemiplegic migraine, a rare subtype of migraine with hemiplegia as an aura.
  • Analyzed clinical features and genetic factors of hemiplegic migraine.
  • Evaluated traditional and emerging treatment strategies including calcium antagonists, anticonvulsants, and CGRP-targeting therapies.
  • Hemiplegic migraine presents with visual and sensory symptoms prior to headaches.
  • Calcium-channel blockers and anticonvulsants show varying efficacy in preventive therapy.
  • CGRP-related antibody therapies report promising treatment outcomes in hemiplegic migraine.

Cite This Study

Shibata et al. (2026) studied this question.

synapsesocial.com/papers/6a12955d48a0ea1665671755https://doi.org/10.5692/clinicalneurol.cn-002244
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